Reconstruction of Gene Regulatory Networks using Multiple Datasets
نویسندگان
چکیده
منابع مشابه
Consensus gene regulatory networks: combining multiple microarray gene expression datasets
In this paper we present a method for modelling gene regulatory networks by forming a consensus Bayesian network model from multiple microarray gene expression datasets. Our method is based on combining Bayesian network graph topologies and does not require any special pre-processing of the datasets, such as re-normalisation. We evaluate our method on a synthetic regulatory network and part of ...
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Microarray data is a key source of experimental data for modelling gene regulatory interactions from expression levels. With the rapid increase of publicly available microarray data comes the opportunity to produce regulatory network models based on multiple datasets. Such models are potentially more robust with greater confidence, and place less reliance on a single dataset. However, combining...
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ژورنال
عنوان ژورنال: IEEE/ACM Transactions on Computational Biology and Bioinformatics
سال: 2021
ISSN: 1545-5963,1557-9964,2374-0043
DOI: 10.1109/tcbb.2021.3057241